History repeats: When the H1N1 flu shot Pandemrix caused narcolepsy

History is repeated. With the recall of AstraZeneca, people are now made to believe that the AstraZeneca vaccination was the only one that really harmed the recipients. However, Moderna and Pfizer have caused significantly more harm.

But the Covid-19 vaccines are not the first to cause harm. Let us go back to what happened back in 2009 when there was the H1N1 influenza pandemic. During those times, a vaccine called Pandemrix was administered in the UK and Scandinavian countries.

Back in 2015, we read how in a paper in Science Translational Medicine (STM)  researchers showed that the vaccine, called Pandemrix, “which was given to more than 30 million Europeans, triggered an autoimmune re action that led to narcolepsy in some people who were genetically at risk.”

Pasi Penttinen, who headed the influenza program at the European Centre for Disease Prevention and Control in Stockholm, stated: “They put together quite a convincing picture and provide a plausible explanation for what has happened. It’s really the kind of work we’ve been waiting for for 5 years.” 

Narcolepsy is an enigmatic illness that affects about one in 3000 people in Europe and usually manifests itself during infancy or adolescence. Hypocretin, a chemical that aids in controlling the sleep-wake cycle, becomes insufficient in patients as a result of specific brain cells in the hypothalamus being lost. Because nearly everyone with the vaccine-associated type of narcolepsy carries a particular version of a gene in the HLA family, which aids the body in differentiating between proteins created by microbes and its own, researchers believe an autoimmune reaction is the reason.

Neuroscientist Lawrence Steinman of Stanford University in Palo Alto, California, and rheumatologist Sohail Ahmed, who was then global head of clinical sciences at Novartis’s vaccines and diagnostics division in Siena, Italy, learned about the 2010 narcolepsy epidemic and immediately started searching databases for proteins expressed in the brain that might be similar to those in the vaccine.

Their investigation yielded a potential culprit: a segment of a hypocretin receptor bears similarities to a portion of the H1N1 influenza nucleoprotein, which attaches itself to the virus genome and is essential for its propagation. Ahmed, who is currently employed by GSK after purchasing a portion of Novartis’s vaccine division, adds, “That was really a ‘Aha’ moment.” The goal of the flu vaccination is to produce antibodies against the surface proteins of influenza, although

Circumstantial evidence suggested earlier by some of the same researchers that the nucleoprotein might be a significant player. Outi Vaarala of the University of Helsinki and her associates had revealed in December that the GSK vaccination Pandemrix had a significantly higher amount of nucleoprotein than Arepanrix, and that the latter was linked to a significantly lower incidence of narcolepsy. The team also discovered that children with narcolepsy reacted differently to the nucleoprotein in Pandemrix in terms of their immune systems.

In the latest study, serum from Pandemrix-treated Finnish narcolepsy patients was given to cells that were surface-engineered to express human hypocretin receptor 2. In 17 out of 20 samples, patient-derived antibodies were linked to these cells. These antibodies were absent from the serum of Italians immunized with the Focetria pandemic vaccine, a separate Novartis product. Additionally, it was demonstrated by the researchers that Focetria, which has not been connected to narcolepsy, had a significantly lower nucleoprotein concentration than Pandemrix.

This shows us that during the H1N1 “pandemic” people were administered different vaccines with one particular vaccine causing narcolepsy, while the other, Focetria, didn’t, because of different concoctions. And needless to say, after this disease was triggered, they came up with the solution to find its cure with new insights were researchers “could explore whether somehow unblocking the receptor might allow the hypocretin system to recover.”

The usual problem-reaction-solution: the problem is that a pandemic is created. The reaction is injecting populations with poison. The solution is we find a cure for the poison that the populations were injected with.

This study also suggested “ways to make influenza vaccines even safer, for instance by keeping the nucleoprotein levels low or removing the specific region of the protein that mimics the receptor. ‘We should do everything to understand the disease mechanism,’ Julkunen says, ‘so that this kind of situation would never be repeated.'”

But history is being repeated and yet, we still find those shills who criticize the Covid-19 vaccination while hailing past vaccines.

https://www.science.org/content/article/why-pandemic-flu-shot-caused-narcolepsy

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